In Kandahar, the 115th regiment's squadron (MiG-21bis) fought together with a squadron of the Soviet 136th regiment (MiG-21PFM then MiG-21SM) and the Afghan 366th Fighter Air Regiment (MiG-17 Fresco).
The second squadron of the 115th Guard Fighter Air Regiment fought from Kandahar in between February 1980 and May 1981. The squadron lost two MiG-21bis Fishbed-L fighter aircraft and one pilot in 1980.
- August 1, 1980, fired with 12,7 mm DShK heavy machine gun during the low-level attack in the Jabal-Usassarj area. The Cheshenko pilot was killed
- November 12, 1980, the MiG-21bis plane crashed. The chief of staff of the squadron of the 115th Guard Regiment, A. A. Prokazin, catapulted into the district of the settlement of Faizabad and was picked up by the helicopters.
The 115th regiment was replaced by the Soviet 27th Fighter Air Regiment from Central Asian Military District in May 1981.